Lisata Therapeutics, Inc. (LSTA) Stock

Lisata Therapeutics, Inc. (LSTA) is a Healthcare stock trading at $1.67 (as of 2026-07-24), with a market capitalization of $15.21M. Figures are sourced from first-party U.S. SEC EDGAR filings and market data.

Lisata Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing cellular therapies to reverse disease and/or promote the regeneration of damaged tissue. Its product candidates include HONEDRA, a recipient of SAKIGAKE designation that is in Phase II clinical trial for the treatment of critical limb ischemia; XOWNA that is in Phase IIb clinical trial for the treatment of coronary microvascular dysfunction; and CLBS201, a CD34+ cell therapy for the treatment of pre-dialysis patients with chronic kidney disease. The company was formerly known as NeoStem, Inc. and changed its name to Caladrius Biosciences, Inc. in June 2015. The company was formerly known as Caladrius Biosciences, Inc. and changed its name to Lisata Therapeutics, Inc. on September 15, 2022. Lisata Therapeutics, Inc. was incorporated in 1980 and is headquartered in Basking Ridge, New Jersey.

Understand Lisata Therapeutics, Inc.: how it makes money

Lisata Therapeutics develops and commercializes cellular therapies, with product candidates in Phase II and Phase IIb clinical trials, aiming to treat conditions by reversing disease and promoting regeneration of damaged tissue.

Because Lisata is a clinical-stage biopharmaceutical company developing cellular therapies through Phase II and Phase IIb trials, its path to profit depends on trial execution and clinical efficacy signals that can support moving candidates toward commercialization (with recent reported revenue at 0.0B).

Business quality (Weak): The key watch items are how its trials progress (enrollment and completion) and whether reported efficacy signals compare favorably versus control groups, but investors also face high development risk and a deeply negative operating margin.

Bull case

  • Strong ASCEND recruitment progress: ASCEND Trial Patients Enrolled is 158.0, with ASCEND Overall Enrollment Completion Percentage at 95.0%.
  • Efficacy signals versus placebo are reported in a related trial readout: For the Six-Month Progression-Free Survival, the Certepetide-Treated Group is 60.8% versus 25.0% for the Placebo-Treated Group.
  • Placebo comparison shows longer median progression-free survival for treated group: Median Progression-Free Survival is 7.5 for the Certepetide-Treated Group versus 4.7 for the Placebo-Treated Group.

Bear case

  • Clinical-stage execution may not translate into approvals: The companys key candidates are in Phase II or Phase IIb clinical trials (with no approval or commercialization proof provided in the facts).
  • Costs remain extremely high relative to current revenue: The latest reported operating margin is -6954.3.
  • Not all trial milestones show complete readiness: Dendifox Enrollment Completion Percentage is 80.0%, which is below the ASCEND completion level.
Valuation — source: SEC EDGAR (first-party)
Price$1.67
Market Cap$15.21M
Price / Book1.43
Price / Sales63.37
FCF Yield-46.1%
Profitability & Growth — source: SEC EDGAR
Revenue (TTM)$170000.00
Net Margin-9756.5%
Return on Equity-153.2%
Current Ratio4.23
Revenue Growth (YoY)-83.0%
EPS Growth (YoY)-20.4%
FCF Growth (YoY)-17.5%
Financial Health — source: SEC EDGAR
Altman Z-Score-44.04 (distress)
Valuation vs Sector & Industry
Sector P/E (Healthcare)21.2
Industry P/E (Pharmaceutical Products)17.0
Smart-Money Activity — SEC Form 4 / 13F / Congressional disclosures
Top Institutional HolderVANGUARD CAPITAL MANAGEMENT LLC ($1.36M)
Institutional Holders Tracked10
Company
SectorHealthcare
IndustryPharmaceutical Products
CEODavid J. Mazzo
Employees26
CountryUS
IPO Date1999-03-01

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LSTA earnings history · LSTA institutional & insider holders · LSTA KPIs & operating metrics · Congress trades · Insider trades · Short interest · Stock screener

Data as of 2026-07-24.

Figures sourced from U.S. Securities and Exchange Commission (SEC EDGAR) filings and market data. Not personalized investment advice.