Prime Medicine, Inc. (PRME) Stock

Prime Medicine, Inc. (PRME) is a Healthcare stock trading at $3.23 (as of 2026-06-18), with a market capitalization of $641.19M and a trailing P/E of -2.9. Figures are sourced from first-party U.S. SEC EDGAR filings and market data.

Prime Medicine, Inc., a biotechnology company, delivers genetic therapies to address diseases by deploying gene editing technology. It offers Prime Editors with a Prime Editor protein, comprising a fusion between a Cas protein and a reverse transcriptase enzyme; and a pegRNA, which targets the Prime Editor to a specific genomic location and provides a template for making the desired edit to the target DNA sequence. The company was incorporated in 2019 and is headquartered in Cambridge, Massachusetts.

Valuation — source: SEC EDGAR (first-party)
Price$3.23
Market Cap$641.19M
P/E Ratio-2.9
EV / EBITDA-2.8
Price / Book8.36
Price / Sales138.43
DCF Value (model)$-15.33
DCF Upside vs Price-574.6%
Profitability & Growth — source: SEC EDGAR
Revenue (TTM)$4.63M
Net Margin-4342.4%
Return on Equity-258.6%
Current Ratio3.80
Revenue Growth (YoY)55.3%
EPS Growth (YoY)-18.2%
FCF Growth (YoY)28.4%
Financial Health — source: SEC EDGAR
Altman Z-Score-3.54 (distress)
Valuation vs Sector & Industry
Stock P/E-2.9
Sector P/E (Healthcare)20.9
Industry P/E (Pharmaceutical Products)17.0
vs Sector-113.8%
vs Industry-117.0%
Smart-Money Activity — SEC Form 4 / 13F / Congressional disclosures
Top Institutional HolderAlphabet Inc. ($57.64M)
Institutional Holders Tracked10
Company
SectorHealthcare
IndustryPharmaceutical Products
CEOAllan Reine
Employees214
CountryUS
IPO Date2022-10-20

Related Companies (Business model: Biotech (Clinical / Commercial-Stage); 8 closest by market cap; US-domiciled)

  • Organogenesis Holdings Inc. (ORGO)
  • Lyell Immunopharma, Inc. (LYEL)
  • Emergent BioSolutions Inc. (EBS)
  • MeiraGTx Holdings plc (MGTX)
  • Gyre Therapeutics, Inc. (GYRE)
  • Cullinan Therapeutics, Inc. (CGEM)
  • SELLAS Life Sciences Group, Inc. (SLS)
  • Corvus Pharmaceuticals, Inc. (CRVS)
PRME earnings history · PRME institutional & insider holders · Congress trades · Insider trades · Short interest · Stock screener

Data as of 2026-06-18.

Figures sourced from U.S. Securities and Exchange Commission (SEC EDGAR) filings and market data. Not personalized investment advice.