BeOne Medicines Ltd. (ONC) Stock

BeOne Medicines Ltd. (ONC) is a Healthcare stock trading at $346.89 (as of 2026-09-11). Figures are sourced from first-party U.S. SEC EDGAR filings and market data.

BeOne Medicines Ltd. is a global oncology company that focuses on discovering, developing, and commercializing cancer therapies. Its portfolio includes Tevimbra (tislelizumab) and Brukinsa (zanubrutinib), with activities spanning internal R&D and externally sourced development, serving patients across multiple regions and cancer types.

Understand BeOne Medicines Ltd.: how it makes money

BeOne Medicines develops and commercializes innovative cancer therapies, making money by selling oncology products such as BRUKINSA and Tevimbra.

BeOne's profit engine is commercial oncology product sales, where high gross margins can support ongoing discovery, development, and commercialization.

Business quality (Solid): Solid product economics are visible in gross margin 89% and operating margin 16%, but the current revenue base is overwhelmingly product-led.

Bull case

  • Commercial momentum is accelerating: Quarterly revenue $1.5B (+35% YoY) shows strong commercial momentum, which can help fund the company's oncology pipeline and expand operating leverage.
  • Drug sales carry strong economics: Gross margin 89% gives the company substantial economics on each product sale, supporting investment in development and commercialization.

Bear case

  • Revenue depends on product sales: Net product revenues $1.5B = 99% of revenue shows that current revenue is overwhelmingly tied to commercial product sales. A setback affecting products or launches could therefore have a direct effect on reported revenue.
Valuation — source: SEC EDGAR (first-party)
Price$346.89
DCF Value (model)$8.60
DCF Upside vs Price-97.5%
Profitability & Growth — source: SEC EDGAR
Revenue (TTM)$5.34B
Net Margin5.4%
Return on Equity12.7%
Debt / Equity0.18
Current Ratio3.40
Revenue Growth (YoY)29.6%
EPS Growth (YoY)128.6%
FCF Growth (YoY)187.2%
Financial Health — source: SEC EDGAR
Altman Z-Score78.49 (safe)
Valuation vs Sector & Industry
Sector P/E (Healthcare)19.4
Industry P/E (Pharmaceutical Products)15.1
Smart-Money Activity — SEC Form 4 / 13F / Congressional disclosures
Top Institutional HolderBAKER BROS. ADVISORS LP ($2.51B)
Institutional Holders Tracked10
Company
SectorHealthcare
IndustryPharmaceutical Products
CEOJohn V. Oyler
Employees11,000
CountryUS
IPO Date2016-02-02

BeOne Medicines Ltd. earnings call transcripts

  • ONC Q4 FY25 earnings call transcript (reported 2026-02-26) · analysis

All ONC earnings calls

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  • Viatris Inc. (VTRS)
  • Gilead Sciences, Inc. (GILD)
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ONC earnings history · ONC institutional & insider holders · ONC KPIs & operating metrics · ONC financials · ONC filings, presentations & press releases · ONC investor presentations & press releases · ONC SEC filings · ONC peers · Congress trades · Insider trades · Short interest · Stock screener

Data as of 2026-09-11.

Figures sourced from U.S. Securities and Exchange Commission (SEC EDGAR) filings and market data. Not personalized investment advice.