MapLight Therapeutics, Inc. (MPLT) Stock

MapLight Therapeutics, Inc. (MPLT) is a Healthcare stock trading at $11.53 (as of 2026-08-21), with a market capitalization of $523.89M. Figures are sourced from first-party U.S. SEC EDGAR filings and market data.

MapLight Therapeutics, Inc. operates as a clinical-stage biopharmaceutical company for patients suffering from debilitating central nervous system disorders. The company's products include ML-007C-MA, a fixed-dose combination of an M 1 /M 4 muscarinic agonist for the treatment of schizophrenia and Alzheimer's disease psychosis; ML-004 for the treatment of social communication deficit and/or irritability in autism spectrum disorder; ML-021 for the treatment of motor deficits in Parkinson's disease; and ML-009, a G-protein-coupled receptor 52 positive allosteric modulator for the treatment of hyperactivity, impulsivity and agitation-related disorders. The company also develops platform identifying neural circuits causally linked to disease and targeting those circuits for therapeutic modulation. MapLight Therapeutics, Inc. was formerly known as Alvarado Therapeutics, Inc. and changed its name to MapLight Therapeutics, Inc. in August 2019. MapLight Therapeutics, Inc. was incorporated in 2018 and is based in Redwood City, California. MapLight Therapeutics, Inc operates as a subsidiary of Catalyst4, Inc.

Understand MapLight Therapeutics, Inc.: how it makes money

MapLight Therapeutics is a clinical-stage biopharmaceutical company developing drug candidates for patients with debilitating central nervous system disorders, and its revenue model is not described in the provided facts.

As a clinical-stage biopharmaceutical company, its path to profitability is structurally tied to successfully advancing specific clinical programs, which is reflected in the reported Phase 2 trial enrollment and randomized participant counts rather than commercial metrics.

Business quality (Weak): The company shows Phase 2 development progress via enrollment and randomization metrics, but the provided financials indicate no reported revenue and a very large negative operating margin, highlighting pre-commercial risk.

Valuation: At 3× earnings, MPLT trades 80% below the Pharmaceutical Products average (17×). Note: one-time items can distort reported P/E.

Bull case

  • Phase 2 progress signal: The company reports ZEPHYR Phase 2 trial enrollment completed for schizophrenia (307.0 count).
  • Clinical execution in another program: It also reports approximately randomized participants in the Phase 2 IRIS study for autism spectrum disorder (161.0 count).

Bear case

  • Pre-commercial financial pressure: In the latest reported period (2026-03-31), revenue is reported as 0.0B.
  • Large operating losses: Operating margin is reported as -2609.3 for the same period, indicating substantial ongoing operating losses.
  • Clinical development uncertainty: Because it is described as clinical-stage and the provided operating indicators are trial enrollment and randomization, outcomes from these studies remain uncertain based on the provided facts.
Valuation — source: SEC EDGAR (first-party)
Price$11.53
Market Cap$523.89M
Price / Book1.50
Price / Sales59.25
FCF Yield-55.3%
Profitability & Growth — source: SEC EDGAR
Revenue (TTM)$5.52M
Net Margin-2920.5%
Revenue Growth (YoY)22.5%
EPS Growth (YoY)-82.4%
FCF Growth (YoY)74.2%
Financial Health — source: SEC EDGAR
Altman Z-Score12.45 (safe)
Valuation vs Sector & Industry
Sector P/E (Healthcare)21.7
Industry P/E (Pharmaceutical Products)17.2
Smart-Money Activity — SEC Form 4 / 13F / Congressional disclosures
Top Institutional HolderNOVO HOLDINGS A/S ($74.95M)
Institutional Holders Tracked10
Company
SectorHealthcare
IndustryPharmaceutical Products
CEOChristopher A. Kroeger
Employees109
CountryUS
IPO Date2025-10-24

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MPLT earnings history · MPLT institutional & insider holders · MPLT KPIs & operating metrics · MPLT financials · MPLT investor presentations & press releases · MPLT SEC filings · MPLT peers · Congress trades · Insider trades · Short interest · Stock screener

Data as of 2026-08-21.

Figures sourced from U.S. Securities and Exchange Commission (SEC EDGAR) filings and market data. Not personalized investment advice.