Lineage Cell Therapeutics, Inc. (LCTX) Stock

Lineage Cell Therapeutics, Inc. (LCTX) is a Healthcare stock trading at $1.08 (as of 2026-08-21), with a market capitalization of $273.14M. Figures are sourced from first-party U.S. SEC EDGAR filings and market data.

Lineage Cell Therapeutics, Inc., a clinical-stage biotechnology company, develops novel cell therapies for the treatment of degenerative diseases in the United States and internationally. The company develops OpRegen, a retinal pigment epithelium cell replacement therapy, which is in Phase I/IIa clinical trial for the treatment of the dry age-related macular degeneration; OPC1, an oligodendrocyte progenitor cell therapy that is in Phase I/IIa multicenter clinical trial for the treatment of acute spinal cord injuries; and VAC2, an allogeneic cancer immunotherapy of antigen-presenting dendritic cells, which is in Phase I clinical trial to treat non-small cell lung cancer. It also offers Renevia, a facial aesthetics product. In addition, the company engages in the research and development of therapeutic products for retinal diseases, neurological diseases, and disorders and oncology. Lineage Cell Therapeutics, Inc. has a collaboration with Orbit Biomedical, Ltd. The company was formerly known as BioTime, Inc. and changed its name to Lineage Cell Therapeutics, Inc. in August 2019. Lineage Cell Therapeutics, Inc. was incorporated in 1990 and is headquartered in Carlsbad, California.

Understand Lineage Cell Therapeutics, Inc.: how it makes money

Lineage Cell Therapeutics develops novel cell therapies for degenerative diseases, including OpRegen for dry age-related macular degeneration, OPC1 for acute spinal cord injuries, and VAC2 for cancer immunotherapy, and it makes money through collaboration and licensing-related revenue (currently reported as zero).

Because the company is clinical-stage with OpRegen, OPC1, and VAC2 in Phase I/IIa trials, near-term results in the form of patient enrollment and early clinical readouts matter most, while current collaboration and licensing revenue is reported as zero.

Revenue by segment (latest quarter)
Collab$0.0B
RoyaltiesLicOther$0.0B

Business quality (Weak): Clear pipeline focus across multiple Phase I/IIa programs and observable trial activity metrics, but the near-term financial model shows zero reported revenue and a very large operating loss, making execution and trial outcomes critical.

Bull case

  • Multiple early-stage programs with active trial participation: OpRegen is in Phase I/IIa and Phase 2a activity is reflected by cohort and site metrics (including Clinical Sites Enrolling in Phase 2a GAlette Study).
  • Early clinical readouts are being tracked: For OpRegen (dry age-related macular degeneration), metrics such as Mean Best Corrected Visual Acuity Gain for Cohort 4 and related structural improvement measures are reported in the available KPI set.

Bear case

  • No reported revenue in the latest quarter: Collaboration Revenue and Royalties, License and Other Revenue are each reported as 0.0 in the provided facts.
  • Very large operating loss: The latest-quarter operating margin is reported as -440.2%, indicating heavy spending relative to reported revenue.
  • Clinical-stage execution risk: All programs are described as being in Phase I/IIa trials, which can carry the risk that efficacy, safety, or trial progression does not meet expectations.
Valuation — source: SEC EDGAR (first-party)
Price$1.08
Market Cap$273.14M
Price / Book4.57
Price / Sales20.88
FCF Yield-8.9%
Profitability & Growth — source: SEC EDGAR
Revenue (TTM)$14.56M
Net Margin-436.5%
Revenue Growth (YoY)-61.3%
EPS Growth (YoY)-107.7%
FCF Growth (YoY)32.4%
Financial Health — source: SEC EDGAR
Altman Z-Score-3.91 (distress)
Valuation vs Sector & Industry
Sector P/E (Healthcare)21.7
Industry P/E (Pharmaceutical Products)17.2
Smart-Money Activity — SEC Form 4 / 13F / Congressional disclosures
Top Institutional HolderBROADWOOD CAPITAL INC ($78.31M)
Institutional Holders Tracked10
Company
SectorHealthcare
IndustryPharmaceutical Products
CEOBrian Culley
Employees70
CountryUS
IPO Date1992-03-05

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LCTX earnings history · LCTX institutional & insider holders · LCTX KPIs & operating metrics · LCTX financials · LCTX investor presentations & press releases · LCTX SEC filings · LCTX peers · Congress trades · Insider trades · Short interest · Stock screener

Data as of 2026-08-21.

Figures sourced from U.S. Securities and Exchange Commission (SEC EDGAR) filings and market data. Not personalized investment advice.