Century Therapeutics, Inc. (IPSC) Stock

Century Therapeutics, Inc. (IPSC) is a Healthcare stock trading at $2.06 (as of 2026-08-21), with a market capitalization of $373.92M. Figures are sourced from first-party U.S. SEC EDGAR filings and market data.

Century Therapeutics, Inc., a biotechnology company, develops transformative allogeneic cell therapies for the treatment of solid tumor and hematological malignancies. The company's lead product candidate is CNTY-101, an allogeneic, induced pluripotent stem cells (iPSCs)-derived chimeric antigen receptors (CAR)-iNK cell therapy targeting CD19 for relapsed, refractory B-cell lymphoma. It is also developing CNTY-103, a CAR-iNK candidate targeting CD133 + EGFR for recurrent glioblastoma; CNTY-102, a CAR-iT targeting CD19 + CD79b for relapsed, refractory B-cell lymphoma and other B-cell malignancies; CNTY-104, a CAR-iT or CAR-iNK multi-specific candidate for acute myeloid leukemia; and CNTY-106, a CAR-iNK or CAR-iT multi-specific candidate for multiple myeloma. Century Therapeutics, Inc. was founded in 2018 and is headquartered in Philadelphia, Pennsylvania.

Understand Century Therapeutics, Inc.: how it makes money

Century Therapeutics develops allogeneic, iPSC-derived cell therapies (CAR-iNK and CAR-iT) for solid tumor and hematological cancers, and it makes money primarily through clinical development progress that can translate into revenue through collaborations.

The company’s profit potential is driven by whether its allogeneic iPSC-derived CAR-iNK and CAR-iT candidates show durable clinical efficacy and safety signals in trials, since operational KPIs are tied to response rates and trial patient outcomes.

Business quality (Weak): Strong focus on differentiated allogeneic iPSC-based cell therapy targets (CD19 for CNTY-101, CD133 plus EGFR for CNTY-103, and CD19 plus CD79b for CNTY-102), but near-term fundamentals show losses (operating margin -33.1) and collaboration revenue is shown as 0.0 in the provided segment candidates.

Bull case

  • Lead program targets a defined lymphoma marker: CNTY-101 is an allogeneic, iPSCs-derived CAR-iNK therapy targeting CD19 for relapsed, refractory B-cell lymphoma.
  • Clinical efficacy signals in reported KPIs: The provided operational KPIs include an Overall Response Rate of 83% and a Complete Response Rate of 33%.
  • Broad development pipeline across multiple cancer targets: The company is also developing CNTY-103 (CAR-iNK targeting CD133 + EGFR for recurrent glioblastoma) and CNTY-102 (CAR-iT targeting CD19 + CD79b for relapsed, refractory B-cell lymphoma and other B-cell malignancies).

Bear case

  • Loss-making operating performance in the latest quarter: For the period ending 2025-09-30, operating margin is -33.1, indicating ongoing operating losses.
  • Limited disclosed revenue drivers in the provided data: The only provided segment candidate is Collaboration Revenue, shown as 0.0, which suggests the quarter’s revenue is not supported by disclosed collaboration revenue in this dataset.
  • Efficacy and safety KPIs are based on relatively small evaluable patient counts: The provided Phase 1 ELiPSE-1 metrics show 12 evaluable preliminary safety patients and 10 evaluable preliminary efficacy patients, which can increase uncertainty around broader outcomes.
Valuation — source: SEC EDGAR (first-party)
Price$2.06
Market Cap$373.92M
Price / Book1.61
Price / Sales1.14
FCF Yield-50.0%
Profitability & Growth — source: SEC EDGAR
Revenue (TTM)$109.16M
Net Margin-8.8%
Revenue Growth (YoY)1556.8%
EPS Growth (YoY)-91.3%
FCF Growth (YoY)-5.0%
Financial Health — source: SEC EDGAR
Altman Z-Score-0.75 (distress)
Valuation vs Sector & Industry
Sector P/E (Healthcare)21.7
Industry P/E (Pharmaceutical Products)17.2
Smart-Money Activity — SEC Form 4 / 13F / Congressional disclosures
Top Institutional HolderRA CAPITAL MANAGEMENT, L.P. ($40.13M)
Institutional Holders Tracked10
Company
SectorHealthcare
IndustryPharmaceutical Products
CEOBrent Pfeiffenberger
Employees140
CountryUS
IPO Date2021-06-18

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IPSC earnings history · IPSC institutional & insider holders · IPSC KPIs & operating metrics · IPSC financials · IPSC investor presentations & press releases · IPSC SEC filings · IPSC peers · Congress trades · Insider trades · Short interest · Stock screener

Data as of 2026-08-21.

Figures sourced from U.S. Securities and Exchange Commission (SEC EDGAR) filings and market data. Not personalized investment advice.