Inovio Pharmaceuticals, Inc. (INO) Stock

Inovio Pharmaceuticals, Inc. (INO) is a Healthcare stock trading at $1.18 (as of 2026-08-21), with a market capitalization of $122.01M. Figures are sourced from first-party U.S. SEC EDGAR filings and market data.

Inovio Pharmaceuticals, Inc., a biotechnology company, focuses on the discovery, development, and commercialization of DNA medicines to treat and protect people from diseases associated with human papillomavirus (HPV), cancer, and infectious diseases. Its DNA medicines platform uses precisely designed SynCon that identify and optimize the DNA sequence of the target antigen, as well as CELLECTRA smart devices technology that facilitates delivery of the DNA plasmids. The company engages in conducting and planning clinical studies of its DNA medicines for HPV-associated precancers, including cervical, vulvar, and anal dysplasia; HPV-associated cancers, such as head and neck, cervical, anal, penile, vulvar, and vaginal; other HPV-associated disorders, including recurrent respiratory papillomatosis; glioblastoma multiforme; prostate cancer; HIV; Ebola; Middle East Respiratory Syndrome (MERS); and Lassa fever. Its partners and collaborators include ApolloBio Corp., AstraZeneca, Beijing Advaccine Biotechnology Co., Ltd., The Bill & Melinda Gates Foundation, Coalition for Epidemic Preparedness Innovations (CEPI), Defense Advanced Research Projects Agency (DARPA), Department of Defense (DoD), HIV Vaccines Trial Network, International Vaccine Institute, Kaneka Eurogentec, Medical CBRN Defense Consortium (MCDC), National Cancer Institute, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Ology Bioservices, the Parker Institute for Cancer Immunotherapy, Plumbline Life Sciences, Regeneron Pharmaceuticals, Thermo Fisher Scientific, University of Pennsylvania, Walter Reed Army Institute of Research, and The Wistar Institute. The company has an agreement with Richter-Helm BioLogics GmbH & Co. KG to support investigational DNA vaccine INO-4800 for COVID-19; and a partnership with International Vaccine Institute and Seoul National University Hospital. The company was founded in 1979 and is headquartered in Plymouth Meeting, Pennsylvania.

Understand Inovio Pharmaceuticals, Inc.: how it makes money

Inovio Pharmaceuticals develops DNA medicines to treat and protect against diseases associated with HPV, cancer, and infectious diseases, using precisely designed SynCon sequences and CELLECTRA smart devices to deliver DNA plasmids, with revenue from collaborative arrangements shown as 0.0 in the latest period provided.

The companys profit model depends on whether its DNA medicines progress through clinical studies with clinically meaningful outcomes, and then achieve commercialization, since there is no revenue reported in the latest period provided and the operating performance remains deeply negative.

Business quality (Weak): Clear clinical efficacy metrics are being tracked, but the latest reported revenue is 0.0 and the operating margin is deeply negative, so near-term financial leverage appears limited until later-stage progress and commercialization.

Bull case

  • High clinical response tied to reduced procedures: Overall Clinical Response Rate (Patients With Decrease in Surgical Interventions) is 81.0 percent, and Second-Year Surgery Reduction Rate (Patients With at Least 50% Reduction in Surgeries) is 86.0 percent.
  • Meaningful response proportions reported: Overall Response Rate (Complete Response Plus Partial Response) is 72.0 percent, with Complete Responders Rate (Zero Surgeries Per Year) at 50.0 percent.

Bear case

  • Adverse events are common in the reported population: Participants Experiencing At Least One Treatment-Emergent Adverse Event is 86.0 percent, and Participants Experiencing Grade Three Treatment-Emergent Adverse Events is 14.0 percent.
  • No revenue and very negative operating economics in the latest period: Revenue is 0.0 for the latest period provided, Operating margin is -38337.0, and Revenue From Collaborative Arrangements is 0.0.
Valuation — source: SEC EDGAR (first-party)
Price$1.18
Market Cap$122.01M
Price / Book27.91
FCF Yield-124.8%
Profitability & Growth — source: SEC EDGAR
Revenue (TTM)$65343.00
Net Margin-130000.0%
Revenue Growth (YoY)-70.0%
EPS Growth (YoY)-54.2%
FCF Growth (YoY)-15.0%
Financial Health — source: SEC EDGAR
Altman Z-Score-36.80 (distress)
Valuation vs Sector & Industry
Sector P/E (Healthcare)21.7
Industry P/E (Pharmaceutical Products)17.0
Smart-Money Activity — SEC Form 4 / 13F / Congressional disclosures
Top Institutional HolderFMR LLC ($16.25M)
Institutional Holders Tracked10
Company
SectorHealthcare
IndustryPharmaceutical Products
CEOJacqueline E. Shea
Employees134
CountryUS
IPO Date1998-12-08

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INO earnings history · INO institutional & insider holders · INO KPIs & operating metrics · INO financials · INO investor presentations & press releases · INO SEC filings · INO peers · Congress trades · Insider trades · Short interest · Stock screener

Data as of 2026-08-21.

Figures sourced from U.S. Securities and Exchange Commission (SEC EDGAR) filings and market data. Not personalized investment advice.