Eton Pharmaceuticals, Inc. (ETON) Stock

Eton Pharmaceuticals, Inc. (ETON) is a Healthcare stock trading at $63.42 (as of 2026-08-21), with a market capitalization of $1.81B and a trailing P/E of 142.9. Figures are sourced from first-party U.S. SEC EDGAR filings and market data.

Eton Pharmaceuticals, Inc., a specialty pharmaceutical company, focuses on developing and commercializing pharmaceutical products for rare diseases. The company offers Biorphen, a phenylephrine injection for the treatment of clinically important hypotension resulting primarily from vasodilation in the setting of anesthesia; Carglumic Acid for the treatment of acute and chronic hyperammonemia due to N-acetylglutamate Synthase deficiency; and Rezipres, a ready-to-use formulation of a molecule that is indicated for the treatment of clinically important hypotension occurring in the setting of anesthesia. It also offers Alkindi Sprinkle, a replacement therapy for adrenocortical insufficiency in children under 17 years of age; EPRONTIA, a liquid formulation of topiramate; and Alaway Preservative Free, a preservative-free ophthalmic product to treat allergic conjunctivitis. In addition, the company develops Zonisamide Oral Suspension for the treatment of partial on-set seizures; Lamotrigine for Oral Suspension for the treatment of partial on-set seizures; cysteine injection; dehydrated alcohol injection; and Zeneo hydrocortisone autoinjector. Eton Pharmaceuticals, Inc. was incorporated in 2017 and is based in Deer Park, Illinois.

Understand Eton Pharmaceuticals, Inc.: how it makes money

Eton Pharmaceuticals develops and commercializes specialty drugs for rare diseases, earning revenue from net product sales and royalty revenues, and also from licensing fees, divestiture-related licensing revenue, and launch milestone revenue.

Eton's profit is structurally driven by a small base of commercial product revenue (net product sales and royalties) combined with additional cash inflows from licensing arrangements and launch milestone payments, so changes in patient demand and milestone timing can swing results.

Revenue by segment (latest quarter)
Products$0.0B
Licensing$0.0B

Business quality (Mixed): The company has positive gross and operating margins in the latest quarter, but the operating picture depends on rare-disease patient metrics and reimbursement, and it also shows meaningful reliance on licensing and on a small set of customers.

Valuation: At 650× earnings, ETON trades 3758% above the Pharmaceutical Products average (17×). Note: one-time items can distort reported P/E.

Bull case

  • Positive profitability signals in the latest quarter: For the period ended 2026-03-31, gross margin was 60.7% and operating margin was 9.9%.
  • Reimbursement support for treated patients: Percent of Treated Patients Reimbursed for the Product was 90%.
  • Revenue comes from both products and structured licensing: Revenue sources shown include Net Product Sales and Royalty Revenues, Licensing Revenue from Hospital Products Divestiture, Aprantia Licensing Fee Revenue, and Azurity Launch Milestone Revenue.

Bear case

  • Customer concentration risk: Customer Concentration - Customer B was 41.4%, and Customer Concentration - Customer C was 15.4%.
  • Small revenue scale in the data provided: The latest-quarter revenue is shown as 0.0B, while the individual revenue line items provided are small (for example, Net Product Sales and Royalty Revenues at 0.02B).
  • Operational dependence on patient-driven demand: Key operating metrics include Active Patients on Therapy (400), Active INCRELEX Patients (100), and Active Alkindi Sprinkle Patients (500), which may change quarter to quarter.
  • Licensing and milestone timing can be lumpy: Licensing-related revenue line items shown include Aprantia Licensing Fee Revenue (0.01B) and Azurity Launch Milestone Revenue (0.01B), which may not repeat on a consistent schedule.
Valuation — source: SEC EDGAR (first-party)
Price$63.42
Market Cap$1.81B
P/E Ratio142.9
EV / EBITDA87.0
Price / Book38.91
Price / Sales17.17
FCF Yield1.9%
DCF Value (model)$13.23
DCF Upside vs Price-79.1%
Profitability & Growth — source: SEC EDGAR
Revenue (TTM)$79.95M
Net Margin-5.8%
Revenue Growth (YoY)98.6%
EPS Growth (YoY)-520.0%
FCF Growth (YoY)-8.8%
Financial Health — source: SEC EDGAR
Altman Z-Score15.16 (safe)
Piotroski F-Score5/9 (moderate)
Valuation vs Sector & Industry
Stock P/E142.9
Sector P/E (Healthcare)21.7
Industry P/E (Pharmaceutical Products)17.2
vs Sector557.3%
vs Industry731.8%
Smart-Money Activity — SEC Form 4 / 13F / Congressional disclosures
Top Institutional HolderOpaleye Management Inc. ($70.58M)
Institutional Holders Tracked10
Company
SectorHealthcare
IndustryPharmaceutical Products
CEOSean E. Brynjelsen
Employees31
CountryUS
IPO Date2018-11-13

Related Companies (Pharmaceutical Products; 8 comparable drugmakers)

  • Arcturus Therapeutics Holdings Inc. (ARCT)
  • CytomX Therapeutics, Inc. (CTMX)
  • Lifecore Biomedical, Inc. (LFCR)
  • Cytokinetics, Incorporated (CYTK)
  • Assembly Biosciences, Inc. (ASMB)
  • Viridian Therapeutics, Inc. (VRDN)
  • Rockwell Medical, Inc. (RMTI)
  • Kura Oncology, Inc. (KURA)
ETON earnings history · ETON institutional & insider holders · ETON KPIs & operating metrics · ETON financials · ETON investor presentations & press releases · ETON SEC filings · ETON peers · Congress trades · Insider trades · Short interest · Stock screener

Data as of 2026-08-21.

Figures sourced from U.S. Securities and Exchange Commission (SEC EDGAR) filings and market data. Not personalized investment advice.