| 2026-08-12 | Presentation | Corporate Presentation |
| 2026-08-12 | Press release | Spruce Biosciences Reports Second Quarter 2026 Financial Results and Provides Corporate Updates |
| 2026-08-12 | Press release | Cure Sanfilippo Foundation and National MPS Society Make $5.5 Million Strategic Investment in Spruce Biosciences |
| 2026-08-03 | Press release | Spruce Biosciences Appoints Jessica Cohen Pfeffer, M.D., as Vice President, Clinical Development |
| 2026-07-27 | Press release | Spruce Biosciences Appoints Adrian Quartel, M.D., FFPM, as Chief Medical Officer |
| 2026-07-08 | Press release | Spruce Biosciences to Participate in the B. Riley Securities 2026 Mind, Muscle & Vision Healthcare Summit |
| 2026-06-29 | Press release | Spruce Biosciences Joins the Russell 3000® Index |
| 2026-06-22 | Press release | Spruce Biosciences Appoints Agnieszka Jurecka, M.D., Ph.D., MPH, as Vice President, Medical Affairs |
| 2026-06-15 | Press release | Spruce Biosciences Appoints Eric Jordan as Vice President, Marketing and Tina Gullotta as Vice President, Finance and Co |
| 2026-06-08 | Press release | Spruce Biosciences Announces Long-Term Tralesinidase Alfa Enzyme Replacement Therapy Data in Sanfilippo Syndrome Type B |
| 2026-05-28 | Press release | Spruce Biosciences Announces Data Presentation at the 18th International MPS Symposium |
| 2026-05-27 | Press release | Spruce Biosciences to Participate in Upcoming Conferences in June |
| Press release | Spruce Biosciences Reports First Quarter 2026 Financial Results and Provides Corporate Updates |
| Press release | Spruce Biosciences Reports Full Year 2025 Financial Results and Provides Corporate Updates |
| 2026-03-02 | Press release | Spruce Biosciences to Present at Upcoming Investor Conferences in March |
| 2026-02-18 | Press release | Spruce Biosciences Announces Positive Type B Meetings with U.S. FDA for TA-ERT for the Treatment of Sanfilippo Syndrome |
| 2026-02-17 | Press release | Spruce Biosciences to Participate in the Oppenheimer 36th Annual Healthcare Life Sciences Conference |
| 2026-02-05 | Press release | Long-Term Data Presented at the 22nd Annual WORLDSymposium™ Highlights Tralesinidase Alfa Enzyme Replacement Therapy’s P |
| 2026-01-28 | Press release | Spruce Biosciences Announces Data Presentations at the 22nd Annual WORLDSymposium™ |
| Press release | Spruce Biosciences Reports Third Quarter 2025 Financial Results and Provides Corporate Updates |
| Press release | Spruce Biosciences Reports Second Quarter 2025 Financial Results and Provides Corporate Updates |
| Press release | Spruce Biosciences Reports First Quarter 2025 Financial Results and Provides Corporate Updates |
| 2024-11-11 | Press release | Spruce Biosciences Reports Third Quarter 2024 Financial Results and Provides Corporate Updates |
| 2024-08-12 | Press release | Spruce Biosciences Reports Second Quarter 2024 Financial Results and Provides Corporate Updates |
| 2024-05-13 | Press release | Spruce Biosciences Reports First Quarter 2024 Financial Results and Provides Corporate Updates |
| 2024-03-13 | Press release | Spruce Biosciences Reports Full Year 2023 Financial Results and Provides Corporate Updates |
| 2023-11-13 | Press release | Spruce Biosciences Reports Third Quarter 2023 Financial Results and Provides Corporate Updates |
| 2023-08-14 | Press release | Spruce Biosciences Reports Second Quarter 2023 Financial Results and Provides Corporate Updates |
| 2023-05-15 | Press release | Spruce Biosciences Reports First Quarter 2023 Financial Results and Provides Corporate Updates |
| 2023-03-16 | Press release | Spruce Biosciences Reports Full Year 2022 Financial Results and Provides Corporate Updates |
| 2022-11-10 | Press release | Spruce Biosciences Reports Third Quarter 2022 Financial Results and Provides Corporate Updates |
| 2022-08-10 | Press release | Spruce Biosciences Reports Second Quarter 2022 Financial Results and Provides Corporate Update |
| 2022-05-11 | Press release | Spruce Biosciences Reports First Quarter 2022 Financial Results and Provides Corporate Update |
| 2022-03-14 | Press release | Spruce Biosciences Reports Fourth Quarter and Full Year 2021 Financial Results and Provides Corporate Updates |
| 2021-11-15 | Press release | Spruce Biosciences Reports Third Quarter 2021 Financial Results and Provides Corporate Updates |
| 2021-08-10 | Press release | Spruce Biosciences Reports Second Quarter 2021 Financial Results and Provides Corporate Updates |
| 2021-05-12 | Press release | Spruce Biosciences Reports First Quarter 2021 Financial Results and Provides Corporate Updates |
| 2021-03-22 | Press release | Spruce Biosciences Reports Fourth Quarter and Full Year 2020 Financial Results and Provides Recent Corporate Updates |
| 2020-11-18 | Press release | Spruce Biosciences Reports Third Quarter 2020 Financial Results and Provides Corporate Update |
| Press release | Spruce Biosciences Announces Key Management and Board Appointments |