Karyopharm Therapeutics Inc. (KPTI) ownership: Top institutional holder: Context Capital Management, LLC ($463.64M). Insider activity: Net Seller (0 buys, 20 sells). SEC EDGAR first-party data.
| Holder | Shares | Market Value | Reported |
|---|---|---|---|
| Context Capital Management, LLC | 62995.00 | $463.64M | 2025-12-31 |
| Commodore Capital LP | 1950000.00 | $10.86M | 2026-03-31 |
| RA CAPITAL MANAGEMENT, L.P. | 1917354.00 | $10.68M | 2026-03-31 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1806322.00 | $10.06M | 2026-03-31 |
| T. Rowe Price Investment Management, Inc. | 1542090.00 | $8.59M | 2026-03-31 |
| Opaleye Management Inc. | 930000.00 | $6.84M | 2025-12-31 |
| Caption Management, LLC | 1086900.00 | $6.05M | 2026-03-31 |
| GOLDMAN SACHS GROUP INC | 947579.00 | $5.28M | 2026-03-31 |
| Insider | Transaction | Value | Date |
|---|---|---|---|
| Sell | null | 2026-05-21 | |
| Sell | null | 2026-05-21 | |
| Sell | null | 2026-05-21 | |
| Sell | null | 2026-05-21 | |
| Sell | null | 2026-05-21 | |
| Sell | null | 2026-05-21 | |
| Sell | null | 2026-05-14 | |
| Sell | null | 2026-05-14 |
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Institutional data from SEC Form 13F. Insider data from SEC Form 4. Congressional data from STOCK Act disclosures. Not personalized investment advice.